Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.84 extracted from

  • Hildebrandt, E.R.; Arachea, B.T.; Wiener, M.C.; Schmidt, W.K.
    Ste24p mediates proteolysis of both isoprenylated and non-prenylated oligopeptides (2016), J. Biol. Chem., 291, 14185-14198 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.84

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0164
-
 Abz-KSKTKC(farnesyl)VIKD at pH 7.5 and 30°C Saccharomyces mikatae
0.0232
-
 K-Ras4b in the absence of insulin B chain, at pH 7.5 and 30°C Saccharomyces mikatae
0.0297
-
 K-Ras4b in the presence of 0.01 mM insulin B chain, at pH 7.5 and 30°C Saccharomyces mikatae
0.0375
-
 K-Ras4b in the presence of 0.02 mM insulin B chain, at pH 7.5 and 30°C Saccharomyces mikatae
0.0375
-
 K-Ras4b in the presence of 0.033 mM insulin B chain, at pH 7.5 and 30°C Saccharomyces mikatae
0.0523
-
 DAEFRHDSGYEVHHQK-(Dabcyl)-LVFFAE-(Edans)-DVGSNK at pH 7.5 and 30°C Saccharomyces mikatae
0.1125
-
 Abz-SEKKDNYIIKGV-(4-nitro)-Y at pH 7.5 and 30°C Saccharomyces mikatae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
a-factor-CaaX + H2O Saccharomyces mikatae
-
 a-factor-C + aaX
-
 ?
prelamin A + H2O Saccharomyces mikatae cleavage occurs between the farnesylated cysteine and the A1 position of the CAAX motif, although the prelamin A peptide is predominantly cleaved between A1 and A2 lamin A + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces mikatae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
a-factor mating pheromone + H2O
-
 Saccharomyces mikatae ?
-
 ?
a-factor-CaaX + H2O
-
 Saccharomyces mikatae a-factor-C + aaX
-
 ?
Abeta 1-40 + H2O
-
 Saccharomyces mikatae ?
-
 ?
Abz-KSKTKC(farnesyl)VIKD + H2O
-
 Saccharomyces mikatae ?
-
 ?
Abz-SEKKDNYIIKGV-(4-nitro)-Y + H2O
-
 Saccharomyces mikatae ?
-
 ?
bovine insulin chain A chain + H2O
-
 Saccharomyces mikatae ?
-
 ?
bovine insulin chain B chain + H2O
-
 Saccharomyces mikatae ?
-
 ?
DAEFRHDSGYEVHHQK-(Dabcyl)-LVFFAE-(Edans)-DVGSNK + H2O
-
 Saccharomyces mikatae ?
-
 ?
human insulin + H2O
-
 Saccharomyces mikatae ?
-
 ?
K-Ras4b + H2O
-
 Saccharomyces mikatae ?
-
 ?
prelamin A + H2O cleavage occurs between the farnesylated cysteine and the A1 position of the CAAX motif, although the prelamin A peptide is predominantly cleaved between A1 and A2 Saccharomyces mikatae lamin A + ?
-
 ?
trans,trans-farnesyl bromide + H2O
-
 Saccharomyces mikatae ?
-
 ?

Synonyms

Synonyms Comment Organism
Ste24p
-
 Saccharomyces mikatae